Phosphinophosphonates and their tris-pivaloyloxymethyl prodrugs reveal a negatively cooperative butyrophilin activation mechanism. R. R. Shippy, X. Lin, S. S. Agabiti, J. Li, B. M. Zangari, B. J. Foust, M. M. Poe, C. H. Hsiao, O. Vinogradova, D. F. Wiemer, and A. J. Wiemer. J Med Chem. 2017. PubMed
A new butyrophilin ligand SAR analysis with mechanistic implications.